Email: info@theranib.com
ALDH1A3 Therapeutic Innovation

Pioneering first-in-class therapies targeting ALDH1A3 to combat tumor growth, metastasis and resistance, providing hope for patients worldwide.

First-of-Its-Kind Therapy

There are currently no ALDH1A3-targeting drugs on the market. Theranib is leading the way with groundbreaking innovation.

Our Impact
Over 1 million patients per year globally could benefit from an ALDH1A3 inhibitor therapy.
1 m+

Key Challenges We SolveAdvancing Cancer Care

Therapy Resistance
Reduces the efficacy of cancer treatments by limiting their capacity to eliminate resilient tumor cells, hindering recovery.
Tumor Progression
Accounts for over 90% of global cancer deaths, driven by the aggressive spread of secondary tumors to distant organs.

Our Impact

Patients annually who could benefit from ALDH1A3-targeted therapies
1 M+
Cancer patients with tumors expressing high ALDH1A3 levels
2 %

AboutNext-Generation Cancer Innovation

Theranib Inc. develops ALDH1A3-focused therapies, advancing personalized medicine by integrating biomarker-driven precision diagnostics to deliver tailored treatments for patients with elevated ALDH1A3 levels. By leveraging cutting-edge research and preclinical models, these therapies ensure accurate targeting of tumor cells without affecting healthy tissue. This approach not only enhances the effectiveness of cancer treatment but also reduces the overall burden on patients undergoing therapy, leading to improved survival rates and quality of life

Our ScienceBuilding the Future of Cancer Therapies

Theranib’s groundbreaking compound, VE3, is a first-in-class ALDH1A3 inhibitor specifically designed to:

VE3 has demonstrated high specificity in preclinical models, effectively targeting tumors with elevated ALDH1A3 levels without impacting healthy cells. Pharmacokinetic studies reveal excellent bioavailability, making it suitable for once-daily dosing with minimal side effects.

Therapeutic FocusAddressing Critical Needs in Oncology

Breast Cancer
Targeting aggressive forms of breast cancer with high ALDH1A3 expression to reduce metastasis and improve survival outcomes.
Lung Cancer
Addressing chemotherapy-resistant non-small cell lung cancers by inhibiting ALDH1A3-driven tumor progression.
Colorectal Cancer
Offering precision therapies to patients with advanced colorectal cancer, focusing on reducing recurrence rates.
Prostate Cancer
Tackling metastatic prostate cancer through ALDH1A3 inhibition to enhance treatment efficacy and reduce drug resistance.
Glioblastoma
Developing innovative treatments for this aggressive brain cancer, with a focus on limiting tumor growth and improving quality of life.
Pancreatic Cancer
Aiming to provide new therapeutic options for one of the most challenging cancers to treat due to its resistance to conventional therapies.
Combination Therapy
Enhancing the effectiveness of standard-of-care treatments by integrating ALDH1A3 inhibitors for synergistic outcomes.

Pipeline TimelineA Strategic Roadmap for Precision Medicine

< 2023

Compound Development and Early Research

2023

Initial Patent Filing

2023

Phase 1: Early Preclinical Work

2023

Funding Secured

2024

US Patent Filing

2024

Phase 2: In Vivo Efficacy Studies

News & PublicationsFrom cutting-edge research to impactful collaborations, explore how we are transforming cancer care worldwide.

The Expanding Role of ALDH1A3 in Cancer
Discover the expanding role of ALDH1A3 in cancer stem cells and its th
ALDH1A3 and Breast Cancer Progression
Explore the pivotal role of ALDH1A3 in breast cancer progression highl
Theranib’s US Patent Published
Theranib Inc. announces the publication of its US patent on January 9,

InvestorsOur Valued Partners in Innovation

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